Journal article

Population-based trends in invasive prenatal diagnosis for ultrasound-based indications: two decades of change from 1994 to 2016

E Lostchuck, A Poulton, J Halliday, L Hui

Ultrasound in Obstetrics and Gynecology | WILEY | Published : 2019

Abstract

Objective: To assess trends in ultrasound-indicated prenatal diagnostic testing performed over the past two decades in the Australian state of Victoria, in the context of rapidly changing practices in aneuploidy screening and chromosome analysis. Methods: This was a retrospective analysis of all ultrasound-indicated prenatal diagnostic testing (amniocentesis and chorionic villus sampling) performed in the state of Victoria between 1994 and 2016. Ultrasound indications for testing included: fetal structural abnormality, fetal death, fetal growth restriction, abnormal amniotic fluid volume, genetic ‘soft marker’ and unspecified ultrasound abnormality. Maternal age, indication for testing, type..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

L.H. was funded by a National Health and Medical Research Council Early Career Fellowship (no. 1105603) and J.H. was funded by a National Health and Medical Research Council Senior Research Fellowship (no. 1021252). Discretionary funding from the Murdoch Children's Research Institute has supported the data collection and reporting over the years, as has the Victorian Department of Health until 2008.